Performance of silica monoliths for basic compounds. Silanol activity
McCalley, D. V. (2011) Performance of silica monoliths for basic compounds. Silanol activity. In: Unger, K. K., Tanaka, N. and Mactejevas, E., eds. (2011) Monolithic silicas in separation science. Weinheim, Germany: Wiley VCH, pp. 173-188. ISBN 9783527325757 Available from: http://eprints.uwe.ac.uk/13890
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The large majority of pharmaceuticals, and in addition many compounds of biomedical significance, contain ionisable basic groups. This chapter considers the analysis of these important compounds on silica monolith columns.