Skip to main content

Research Repository

Advanced Search

Breath ammonia analysis: Clinical application and measurement

Hibbard, Troy; Killard, Anthony

Breath ammonia analysis: Clinical application and measurement Thumbnail


Authors

Troy Hibbard



Abstract

This review covers in detail the complexity of human breath, how the body metabolizes ammonia, clinical conditions which are directly related to the regulation of ammonia concentration, and analysis of current techniques that are capable of detecting breath ammonia. Focusing on these areas provides the information needed to develop a breath ammonia sensor for monitoring dysfunction of the human body. Human breath has been broken down into its key components which are necessary for proper understanding of what to look for when attempting to isolate volatile organic compounds. A pathway has been shown which explains the origin of ammonia in the body and how it is processed within a healthy system. Following this, the hazards of several dysfunctions related to the broken ammonia pathway have been discussed. It is essential that technicians have knowledge of these inner workings of the human body along with current technology. Thus, the advantages and disadvantages of techniques from chemical ionization, gas chromatography, laser spectroscopy, and chemical sensing have been discussed. © Taylor and Francis Group, LLC.

Citation

Hibbard, T., & Killard, A. (2011). Breath ammonia analysis: Clinical application and measurement. Critical Reviews in Analytical Chemistry, 41(1), 21-35. https://doi.org/10.1080/10408347.2011.521729

Journal Article Type Article
Publication Date Jan 1, 2011
Deposit Date Jun 7, 2011
Publicly Available Date Nov 15, 2016
Journal Critical Reviews in Analytical Chemistry
Print ISSN 1040-8347
Electronic ISSN 1547-6510
Publisher Taylor & Francis
Peer Reviewed Peer Reviewed
Volume 41
Issue 1
Pages 21-35
DOI https://doi.org/10.1080/10408347.2011.521729
Keywords breath ammonia analysis, ammonia metabolism, clinical applications, analytical techniques
Public URL https://uwe-repository.worktribe.com/output/968963
Publisher URL http://dx.doi.org/10.1080/10408347.2011.521729

Files

1_-_Breath_Ammonia_Review_-_Original_Full_Length_Manuscript.doc (1.7 Mb)
Document


1_-_Breath_Ammonia_Review_-_Original_Full_Length_Manuscript.pdf (732 Kb)
PDF





You might also like



Downloadable Citations