Alastair D. Hay
Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): Randomised controlled trial
Hay, Alastair D.; Costelloe, C�ire; Redmond, Niamh M.; Montgomery, Alan A.; Peters, Tim J.; Fletcher, Margaret; Hollinghurst, Sandra
Authors
C�ire Costelloe
Niamh M. Redmond
Alan A. Montgomery
Tim J. Peters
Margaret Fletcher
Sandra Hollinghurst
Abstract
Objective: To investigate whether paracetamol (acetaminophen) plus ibuprofen are superior to either drug alone for increasing time without fever and the relief of fever associated discomfort in febrile children managed at home. Design: Individually randomised, blinded, three arm trial. Setting: Primary care and households in England. Participants: Children aged between 6 months and 6 years with axillary temperatures of at least 37.8°C and up to 41.0°C. Intervention: Advice on physical measures to reduce temperature and the provision of, and advice to give, paracetamol plus ibuprofen, paracetamol alone, or ibuprofen alone. Main outcome measures: Primary outcomes were the time without fever (
Citation
Peters, T. J., Montgomery, A. A., Redmond, N. M., Costelloe, C., Hay, A. D., Fletcher, M., & Hollinghurst, S. (2008). Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): Randomised controlled trial. BMJ, 337(7672), 729-733. https://doi.org/10.1136/bmj.a1302
Journal Article Type | Article |
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Publication Date | Sep 27, 2008 |
Deposit Date | Jun 29, 2011 |
Publicly Available Date | Dec 2, 2016 |
Journal | BMJ |
Print ISSN | 0959-8138 |
Publisher | BMJ Publishing Group |
Peer Reviewed | Peer Reviewed |
Volume | 337 |
Issue | 7672 |
Pages | 729-733 |
DOI | https://doi.org/10.1136/bmj.a1302 |
Keywords | paracetamol, ibuprofen, treatment, fever, children, (PITCH) |
Public URL | https://uwe-repository.worktribe.com/output/1018988 |
Publisher URL | http://dx.doi.org/10.1136/bmj.a1302 |
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