Self-management of fatigue in rheumatoid arthritis: A randomised controlled trial of group cognitive-behavioural therapy

Hewlett, S., Ambler, N., Almeida, C., Cliss, A., Hammond, A., Kitchen, K., Knops, B., Pope, D., Spears, M., Swinkels, A. and Pollock, J. (2011) Self-management of fatigue in rheumatoid arthritis: A randomised controlled trial of group cognitive-behavioural therapy. Annals of Rheumatic Disease, 70 (6). pp. 1060-1067. ISSN 0003-4967

[img]
Preview
PDF - Published Version
234kB

Publisher's URL: http://dx.doi.org/10.1136/ard.2010.144691

Abstract

Objectives: To investigate the effect of group cognitive behavioural therapy (CBT) for fatigue self-management, compared with groups receiving fatigue information alone, on fatigue impact among people with rheumatoid arthritis (RA). Methods: Two-arm, parallel randomised controlled trial in adults with RA, fatigue ≥6/10 (Visual Analogue Scale (VAS) 0–10, high bad) and no recent change in RA medication. Group CBT for fatigue self-management comprised six (weekly) 2 h sessions, and consolidation session (week 14). Control participants received fatigue self-management information in a 1 h didactic group session. Primary outcome at 18 weeks was the impact of fatigue measured using two methods (Multi-dimensional Assessment of Fatigue (MAF) 0–50; VAS 0–10), analysed using intention-to-treat analysis of covariance with multivariable regression models. Results: Of 168 participants randomised, 41 withdrew before entry and 127 participated. There were no major baseline differences between the 65 CBT and 62 control participants. At 18 weeks CBT participants reported better scores than control participants for fatigue impact: MAF 28.99 versus 23.99 (adjusted difference −5.48, 95% CI −9.50 to −1.46, p=0.008); VAS 5.99 versus 4.26 (adjusted difference −1.95, 95% CI −2.99 to −0.90, p<0.001). Standardised effect sizes for fatigue impact were MAF 0.59 (95% CI 0.15 to 1.03) and VAS 0.77 (95% CI 0.33 to 1.21), both in favour of CBT. Secondary outcomes of perceived fatigue severity, coping, disability, depression, helplessness, self-effi cacy and sleep were also better in CBT participants. Conclusions: Group CBT for fatigue self-management in RA improves fatigue impact, coping and perceived severity, and well-being. Trial registration: ISRCTN 32195100

Item Type:Article
Additional Information:Open Access paid for
Uncontrolled Keywords:rheumatoid arthritis, fatigue, cognitive behavioural therapy, randomized controlled trial
Faculty/Department:Faculty of Health and Applied Sciences
ID Code:15335
Deposited By: Professor S. Hewlett
Deposited On:19 Jul 2011 09:18
Last Modified:21 Sep 2013 04:33

Request a change to this item

Total Document Downloads in Past 12 Months

Document Downloads

Total Document Downloads

More statistics for this item...
Copyright 2013 © UWE better together