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The electrochemical behavior of nitrazepam at a screen-printed carbon electrode and its determination in beverages by adsorptive stripping voltammetry

McGuire, Natasha D.; Honeychurch, Kevin C.; Hart, John P.

Authors

Natasha D. McGuire



Abstract

The cyclic voltammetric behavior of nitrazepam was investigated at screen-printed carbon electrodes over the range1.5 V to {thorn}1.5 V. Two reduction peaks were observable on the negative scan, at 0.7 V, and 1.2 V using pH 6 buffer. On the return scan a single oxidation peak was obtained at 0.05 V. For quantitative analysis of beverages, we developed an anodic adsorptive stripping voltammetric method which required only dilution with buffer. The identification of nitrazepam and flunitrazepam could be achieved using cyclic voltammetry.© 2009 Wiley-VCH Verlag GmbH& Co. KGaA, Weinheim.

Citation

McGuire, N. D., Honeychurch, K. C., & Hart, J. P. (2009). The electrochemical behavior of nitrazepam at a screen-printed carbon electrode and its determination in beverages by adsorptive stripping voltammetry. Electroanalysis, 21(19), 2165-2170. https://doi.org/10.1002/elan.200904667

Journal Article Type Article
Publication Date Oct 1, 2009
Deposit Date Apr 16, 2012
Journal Electroanalysis
Print ISSN 1040-0397
Electronic ISSN 1521-4109
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 21
Issue 19
Pages 2165-2170
DOI https://doi.org/10.1002/elan.200904667
Keywords adsorptive stripping, voltammetry, benzodiazepine, beverages, cyclic voltammetry, screen-printed electrodes, medicinal chemistry
Public URL https://uwe-repository.worktribe.com/output/993369
Publisher URL http://dx.doi.org/10.1002/elan.200904667
Related Public URLs http://onlinelibrary.wiley.com/doi/10.1002/elan.200904667/abstract