Clinical evidence of parietal cortex dysfunction and correlation with extent of allodynia in Complex Regional Pain Syndrome (CRPS) Type 1

Cohen, H. , McCabe, C. , Harris, N. , Hall, J. , Lewis, J. and Blake, D. (2012) Clinical evidence of parietal cortex dysfunction and correlation with extent of allodynia in Complex Regional Pain Syndrome (CRPS) Type 1. To be published in European Journal of Pain. ISSN 1532-2149 [In Press]

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Publisher's URL: http://onlinelibrary.wiley.com/journal/10.1002/(IS...

Abstract

- What's already known about this topic? There is increasing neuroimaging evidence of parietal lobe involvement in CRPS. Severe tactile allodynia and unusual symptoms such as body dysmorphia and finger agnosia have also been documented. - What does this study add? Clinical evidence was found for parietal lobe dysfunction in CRPS. Cortical network dysfunction in CRPS may involve parietal areas, and could provide a rationale explanation for otherwise unusual symptoms and signs. The extent of tactile allodynia correlated with the severity of parietal dysfunction, suggesting a role for maladaptive neuroplasticity.

Item Type:	Article
Uncontrolled Keywords:	parietal cortex, Complex Regional Pain Syndrome, allodynia, allochiria, neurogenic inflammation
Faculty/Department:	Faculty of Health and Life Sciences > Department of Nursing and Midwifery ~Pre-2012 Faculty Structure > Faculty of Health and Life Sciences > Department of Nursing and Midwifery ~Pre-2012 Faculty Structure > Faculty of Health and Life Sciences > Centre for Clinical and Health Services Research
ID Code:	17079
Deposited By:	Professor C. Mccabe
Deposited On:	06 Aug 2012 15:46
Last Modified:	19 Feb 2013 14:49