On the evolution of Boolean networks for computation: A guide RNA mechanism

Bull, L. (2016) On the evolution of Boolean networks for computation: A guide RNA mechanism. International Journal of Parallel, Emergent and Distributed Systems, 31 (2). pp. 101-113. ISSN 1744-5760 Available from: http://eprints.uwe.ac.uk/25784

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Publisher's URL: http://dx.doi.org/10.1080/17445760.2015.1057590

Abstract/Description

There is a growing body of work within computational intelligence which explores the use of representations inspired by the genetic regulatory networks of biological cells. This paper uses a recently presented abstract, tunable model of such networks to investigate how their design through simulated evolution is affected through the ability to dynamically re-wire connectivity. The contextual editing of transcribed RNA by other molecules such that the form of the final product differs from that specified in the corresponding DNA sequence is ubiquitous. It is here shown that a guide RNA-inspired editing mechanism can be selected for under various scenarios.

Item Type:Article
Additional Information:This is an Accepted Manuscript of an article published by Taylor & Francis in International Journal of Parallel, Emergent and Distributed Systems on 15 July 2015, available online: http://wwww.tandfonline.com/10.1080/17445760.2015.1057590
Uncontrolled Keywords:evolution, Boolean network
Faculty/Department:Faculty of Environment and Technology > Department of Computer Science and Creative Technologies
ID Code:25784
Deposited By: Professor L. Bull
Deposited On:17 Jun 2015 10:10
Last Modified:29 Jul 2016 03:50

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