Chromosome translocations and covert leukemic clones are generated during normal fetal development

Mori, H. (2002) Chromosome translocations and covert leukemic clones are generated during normal fetal development. PNAS, 99 (12). pp. 8242-8247. ISSN 0027-8424

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Publisher's URL: http://dx.doi.org/10.1073/pnas.112218799


Item Type:Article
Additional Information:This paper provided molecular biologic evidence indicating that most cases of acute leukaemia in infants are initiated by chromosomal and genetic alterations prenatally, although leukaemia initiation by chromosomal changes was far more common than the rarity of the disease would suggest and giving rise to the multi-hit theory.
Uncontrolled Keywords:chromosome translocations, covert leukemic clones, normal fetal development
Faculty/Department:Faculty of Environment and Technology
~Pre-2012 Faculty Structure > Faculty of Environment and Technology
~Pre-2010 Faculty Structure > Environment and Technology > Bristol Institute of Technology
ID Code:5808
Deposited By: R. Upload account
Deposited On:22 Jan 2010 15:10
Last Modified:22 Nov 2012 15:35

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