Modulation of the fish immune system by hormones

Harris, J. and Bird, D. J. (2000) Modulation of the fish immune system by hormones. Veterinary Immunology and Immunopathology, 77 (3-4). pp. 163-176. ISSN 0165-2427 Available from:

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Immune–neuroendocrine interactions in fish, as in mammals, have become a focus of considerable interest, with the modulation of immune responses by hormones receiving particular attention. Cortisol, growth hormone (GH), prolactin (PRL), reproductive hormones, melanin-concentrating hormone (MCH) and proopiomelanocortin (POMC)-derived peptides have all been shown to influence immune functions in a number of fish species. This review summarises the known effects of these hormones on the fish immune system, as well as the often complex interactions between different hormones. The possible implications for fish health, with respect to aquaculture and the changes in immunocompetence that take place during different stages in the fish life cycle are also discussed.

Item Type:Article
Uncontrolled Keywords:neuroendocrine system, fish immune system, hormones, stress, POMC
Faculty/Department:Faculty of Health and Applied Sciences > Department of Applied Sciences
ID Code:7024
Deposited By: H. Hammond
Deposited On:10 Aug 2010 07:38
Last Modified:16 Nov 2016 00:30

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