Current considerations for the effective safety evaluation of drugs in vitro

Xu, J. and Jackson, S. K. (2009) Current considerations for the effective safety evaluation of drugs in vitro. Mini Reviews in Medicinal Chemistry, 9 (7). pp. 861-868. ISSN 1389-5575

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Publisher's URL: http://dx.doi.org/10.2174/138955709788452577

Abstract

As the traditional in vivo tests are gradually shifting into in vitro tests, some new issues become apparent. This review discusses the essential considerations in endpoint selection, cell model quality, exposure concentration and linking factors between in vitro and in vivo studies in using in vitro models in risk assessment.

Item Type:Article
Faculty/Department:Faculty of Health and Life Sciences > Department of Applied Sciences
~Pre-2012 Faculty Structure > Faculty of Health and Life Sciences > Department of Applied Sciences
~Pre-2010 Faculty Structure > Health and Life Sciences > School of Life Sciences
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ID Code:7125
Deposited By: H. Hammond
Deposited On:19 Jul 2010 08:53
Last Modified:18 Feb 2013 15:52

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