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Number of items: 19.

Article

Anderson, E., Conway, M. E., Alloush, H., O'Malley, K., Smith, A., Ashley, M., Ruddock, M., Reid, C., Lamont, J., Fitzgerald, P., Smith, G., Mehta, P. and Salisbury, V. (2014) Investigation and verification of a bioluminescent biosensor for the quantitation of ara-CTP generation: A biomarker for cytosine arabinoside sensitivity in acute myeloid leukaemia. Biosensors and Bioelectronics, 52. pp. 345-353. ISSN 0956-5663

Hull, J., Hindy, M., Kehoe, P., Chalmers, K., Love, S. and Conway, M. E. (2012) Distribution of the branched chain aminotransferase proteins in the human brain and their role in glutamate regulation. Journal of Neurochemistry, 123 (6). pp. 997-1009. ISSN 1471-4159

Coles, S., Hancock, J. T. and Conway, M. E. (2011) Differential redox potential between the human cytosolic and mitochondrial branched-chain aminotransferase (hBCAT). Acta Biochimica et Biophysica Sinica, 44 (2). pp. 172-176. ISSN 1745-7270

Coles, S. J., Easton, P., Sharrod, H., Hutson, S. M., Hancock, J. T., Patel , V. and Conway, M. E. (2009) S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation. Biochemistry, 48 (3). pp. 645-656. ISSN 0006-2960

Coles, S. J., Easton, P., Sharrod, H., Hutson, S. M., Hancock, J. T., Patel, V. B. and Conway, M. E. (2009) S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation. Biochemistry, 48 (3). pp. 645-656. ISSN 0006-2960

Conway, M. E., Coles, S. J., Islam, M. M. and Hutson, S. M. (2008) Regulatory control of human cytosolic branched-chain aminotransferase by oxidation and S-glutathionylation and its interactions with redox sensitive neuronal proteins. Biochemistry, 47 (19). pp. 5465-5479. ISSN 0006-2960

Islam, M. M., Wallin, R., Wynn, R. M., Conway, M. E., Fujii, H., Mobley, J. A., Chuang, D. T. and Hutson, S. M. (2007) A novel branched-chain amino acid metabolon: Protein-protein interactions in a supramolecular complex. The Journal of Biological Chemistry, 282 (16). pp. 11893-11903.

Yennawar, N. H., Islam, M. M., Conway, M. E., Wallin, R. and Hutson, S. M. (2006) Human mitochondrial branched chain aminotransferase isozyme: Structural role of the CXXC center in catalysis. The Journal of Biological Chemistry, 281. pp. 39660-39671.

Goto, M., Miyahara, I., Hirotsu, K., Conway, M. E., Yennawar, N. H., Islam, M. M. and Hutson, S. M. (2005) Structural determinants for branched-chain aminotransferase isozyme specific inhibition by the anticonvulsant drug gabapentin. The Journal of Biological Chemistry, 280. pp. 37246-37256.

Conway, M. E., Poole, L. B. and Hutson, S. M. (2004) Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme. Biochemistry, 43 (23). pp. 7356-7364. ISSN 0006-2960

Cooper, A., Bruschi, S., Conway, M. E. and Hutson, S. M. (2003) Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-Conjugate beta-lyases, but turnover leads to inactivation. Biochemical Pharmacology, 65 (2). pp. 181-192. ISSN 006-2952

Conway, M. E., Yennawar, N. H., Wallin, R., Poole, L. B. and Hutson, S. M. (2003) Human mitochondrial branched chain aminotransferase (hBCATm): Structural basis for substrate specificity and role of redox active cysteines. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1647 (1-2). pp. 61-65.

Cooper, A., Conway, M. E. and Hutson, S. M. (2002) A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferase. Analytical Biochemistry, 308 (1). pp. 100-105. ISSN 0003-2697

Yennawar, N. H., Conway, M. E., Yennawar, H. P., Farber, G. K. and Hutson, S. M. (2002) Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: Ketamine and pyridoximine phosphate forms. Biochemistry, 41 (39). pp. 11592-11601. ISSN 0006-2960

Conway, M. E., Yennawar, N., Wallin, R., Poole, L. B. and Hutson, S. M. (2002) Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase. Biochemistry, 41 (29). pp. 9070-9078. ISSN 0006-2960

LaNoue, K., Berkich, D., Conway, M. E., Barber, A., Hu, L., Taylor, C. and Hutson, S. M. (2001) Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina. Journal of Neuroscience Research, 66 (5). pp. 914-922. ISSN 0360-4012

Yennawar, N., Conway, M. E., Dunbar, J., Hutson, S. M. and Farber, J. (2001) The structure of human mitochondrial branched chain aminotransferase. Acta Crystallograhica Section D Biological Crystallography, 57 (4). pp. 506-515.

Book Section

Hutson, S. M., Poole, L. B., Coles, S. and Conway, M. E. (2009) Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase. In: (2009) Redox-Mediated Signal Transduction. (Volume) Humana Press (Springer Imprint), pp. 135-148. ISBN 978-1-58829-842-3

Hutson, S. M., Poole, L. B. and Conway, M. E. (2008) Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chaim aminotransferase. In: Hancock, J. T., ed. (2008) Redox-Mediated Signal Transduction: Methods and Protocols. (Volume) Humana Press, pp. 135-148. ISBN 978-1588298423

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