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Number of items: 29.

Article

Ashby, E., Kierzkowska, M., Hull, J., Kehoe, P., Hutson, S. and Conway, M. E. (2016) Altered expression of human mitochondrial branched chain aminotransferase in dementia with lewy bodies and vascular dementia. Neurochemical Research. ISSN 0364-3190 Available from: http://eprints.uwe.ac.uk/27511

Conway, M. E., Hull, J., El Hindy, M., Taylor, S., El Amraoui, F., Paton-Thomas, C., White, P., Williams, H., Haynes, H., Bertoni, A., Radlwimmer, B., Hutson, S. and Kurian, K. (2016) Decreased expression of the mitochondrial bcat protein correlates with improved patient survival in idh-wt gliomas. Brain Pathology. ISSN 1015-6305 Available from: http://eprints.uwe.ac.uk/27510

Conway, M. E. and Lee, C. (2015) The redox switch that regulates molecular chaperones. Biomolecular Concepts, 6 (4). pp. 269-284. ISSN 1868-5021 Available from: http://eprints.uwe.ac.uk/27637

Hull, J., Patel, V. B., Hutson, S. M. and Conway, M. E. (2015) New insights into the role of the branched-chain aminotransferase proteins in the human brain. Journal of Neuroscience Research, 93 (7). pp. 987-998. ISSN 0360-4012 Available from: http://eprints.uwe.ac.uk/25586

Hull, J., Patel, V., El Hindy, M., Lee, C., Odeleye, E., Hezwani, M. ed, Love, S., Kehoe, P., Chalmers, K. and Conway, M. E. (2015) Regional increase in the expression of the BCAT proteins in Alzheimer's disease brain: Implications in glutamate toxicity. Journal of Alzheimer's Disease, 45 (3). pp. 891-905. ISSN 1387-2877 Available from: http://eprints.uwe.ac.uk/25593

Conway, M. E. and Harris, M. (2015) S-nitrosylation of the thioredoxin-like domains of protein disulphide isomerase and its role in neurodegenerative conditions. Frontiers in Chemistry, 3 (27). ISSN 2296-2646 Available from: http://eprints.uwe.ac.uk/27509

El Hindy, M., Hezwani, M., Corry, D., Hull, J., El Amraoui, F., Harris, M., Lee, C. S., Forshaw, T., Wilson, A., Mansbridge, A., Hassler, M., Patel, V. B., Kehoe, P. G., Love, S. and Conway, M. E. (2014) The branched-chain aminotransferase proteins: Novel redox chaperones for protein disulfide isomerase--implications in Alzheimer's disease. Antioxidants & Redox Signaling, 20 (16). pp. 2497-2513. ISSN 1523-0864 Available from: http://eprints.uwe.ac.uk/22049

Anderson, E., Conway, M. E., Alloush, H., O'Malley, K., Smith, A., Ashley, M., Ruddock, M., Reid, C., Lamont, J., Fitzgerald, P., Smith, G., Mehta, P. and Salisbury, V. (2014) Investigation and verification of a bioluminescent biosensor for the quantitation of ara-CTP generation: A biomarker for cytosine arabinoside sensitivity in acute myeloid leukaemia. Biosensors and Bioelectronics, 52. pp. 345-353. ISSN 0956-5663 Available from: http://eprints.uwe.ac.uk/21585

Anderson, E., Smith, M. A., Martin, A., Ruddock, M., Lamont, J., Alloush, H., Conway, M. E., Mehta, P., Smith, J. G. and Salisbury, V. (2013) A novel bioluminescent bacterial biosensor for measurement of Ara-CTP and cytarabine potentiation by fludarabine in seven leukaemic cell lines. Leukemia Research, 37 (6). pp. 690-696. ISSN 0145-2126 Available from: http://eprints.uwe.ac.uk/21670

Hull, J., Hindy, M. E., Kehoe, P. G., Chalmers, K., Love, S. and Conway, M. E. (2012) Distribution of the branched chain aminotransferase proteins in the human brain and their role in glutamate regulation. Journal of Neurochemistry, 123 (6). pp. 997-1009. ISSN 1471-4159 Available from: http://eprints.uwe.ac.uk/18932

Coles, S., Hancock, J. T. and Conway, M. E. (2012) Differential redox potential between the human cytosolic and mitochondrial branched-chain aminotransferase. Acta Biochimica et Biophysica Sinica, 44 (2). pp. 172-176. ISSN 1745-7270 Available from: http://eprints.uwe.ac.uk/16468

Coles, S. J., Easton, P., Sharrod, H., Hutson, S. M., Hancock, J. T., Patel , V. and Conway, M. E. (2009) S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation. Biochemistry, 48 (3). pp. 645-656. ISSN 0006-2960 Available from: http://eprints.uwe.ac.uk/13767

Coles, S. J., Easton, P., Sharrod, H., Hutson, S. M., Hancock, J. T., Patel, V. B. and Conway, M. E. (2009) S-Nitrosoglutathione inactivation of the mitochondrial and cytosolic BCAT proteins: S-nitrosation and S-thiolation. Biochemistry, 48 (3). pp. 645-656. ISSN 0006-2960 Available from: http://eprints.uwe.ac.uk/7937

Conway, M. E., Coles, S. J., Islam, M. M. and Hutson, S. M. (2008) Regulatory control of human cytosolic branched-chain aminotransferase by oxidation and S-glutathionylation and its interactions with redox sensitive neuronal proteins. Biochemistry, 47 (19). pp. 5465-5479. ISSN 0006-2960 Available from: http://eprints.uwe.ac.uk/7952

Islam, M. M., Wallin, R., Wynn, R. M., Conway, M. E., Fujii, H., Mobley, J. A., Chuang, D. T. and Hutson, S. M. (2007) A novel branched-chain amino acid metabolon: Protein-protein interactions in a supramolecular complex. Journal of Biological Chemistry, 282. pp. 11893-11903. ISSN 0021-9258 Available from: http://eprints.uwe.ac.uk/7951

Yennawar, N. H., Islam, M. M., Conway, M. E., Wallin, R. and Hutson, S. M. (2006) Human mitochondrial branched chain aminotransferase isozyme: Structural role of the CXXC center in catalysis. Journal of Biological Chemistry, 281. pp. 39660-39671. ISSN 0021-9258 Available from: http://eprints.uwe.ac.uk/7950

Goto, M., Miyahara, I., Hirotsu, K., Conway, M. E., Yennawar, N. H., Islam, M. M. and Hutson, S. M. (2005) Structural determinants for branched-chain aminotransferase isozyme specific inhibition by the anticonvulsant drug gabapentin. Journal of Biological Chemistry, 280. pp. 37246-37256. ISSN 0021-9258 Available from: http://eprints.uwe.ac.uk/7949

Conway, M. E., Poole, L. B. and Hutson, S. M. (2004) Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme. Biochemistry, 43 (23). pp. 7356-7364. ISSN 0006-2960 Available from: http://eprints.uwe.ac.uk/7948

Conway, M. E., Yennawar, N. H., Wallin, R., Poole, L. B. and Hutson, S. M. (2003) Human mitochondrial branched chain aminotransferase (hBCATm): Structural basis for substrate specificity and role of redox active cysteines. Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1647 (1-2). pp. 61-65. ISSN 0006-3002 Available from: http://eprints.uwe.ac.uk/7947

Cooper, A., Bruschi, S., Conway, M. E. and Hutson, S. M. (2003) Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-Conjugate beta-lyases, but turnover leads to inactivation. Biochemical Pharmacology, 65 (2). pp. 181-192. ISSN 006-2952 Available from: http://eprints.uwe.ac.uk/7945

Cooper, A. J. L., Conway, M. E. and Hutson, S. M. (2002) A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferase. Analytical Biochemistry, 308 (1). pp. 100-105. ISSN 0003-2697 Available from: http://eprints.uwe.ac.uk/7943

Yennawar, N. H., Conway, M. E., Yennawar, H. P., Farber, G. K. and Hutson, S. M. (2002) Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: Ketimine and pyridoximine phosphate forms. Biochemistry, 41 (39). pp. 11592-11601. ISSN 0006-2960 Available from: http://eprints.uwe.ac.uk/7944

Conway, M. E., Yennawar, N., Wallin, R., Poole, L. B. and Hutson, S. M. (2002) Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase. Biochemistry, 41 (29). pp. 9070-9078. ISSN 0006-2960 Available from: http://eprints.uwe.ac.uk/7942

LaNoue, K., Berkich, D., Conway, M. E., Barber, A., Hu, L., Taylor, C. and Hutson, S. M. (2001) Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina. Journal of Neuroscience Research, 66 (5). pp. 914-922. ISSN 0360-4012 Available from: http://eprints.uwe.ac.uk/7941

Yennawar, N., Conway, M. E., Dunbar, J., Hutson, S. M. and Farber, J. (2001) The structure of human mitochondrial branched chain aminotransferase. Acta Crystallograhica Section D Biological Crystallography, 57 (4). pp. 506-515. Available from: http://eprints.uwe.ac.uk/7940

Book Section

Conway, M. E. and Hutson, S. (2015) The cytosolic and mitochondrial branched-chain aminotransferase. In: Rajendram, R., Preedy, V. R. and Patel, V. B., eds. (2015) Branched Chain Amino Acids in Clinical Nutrition. (1) Springer, pp. 25-40. ISBN 9781493919222 Available from: http://eprints.uwe.ac.uk/27507

Conway, M. E. (2011) Aminotransferases. In: D'Mello, J., ed. (2011) Amino Acids in Human Nutrition and Health. CABI, pp. 24-41. ISBN 9781845937980 Available from: http://eprints.uwe.ac.uk/27500

Hutson, S. M., Poole, L. B., Coles, S. and Conway, M. E. (2009) Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase. In: Hancock, J. T., ed. (2009) Redox-Mediated Signal Transduction. (476) Humana Press (Springer Imprint), pp. 135-148. ISBN 9781588298423 Available from: http://eprints.uwe.ac.uk/7936

Hutson, S. M., Poole, L. B. and Conway, M. E. (2008) Redox regulation and trapping sulphenic acid in the peroxide sensitive human mitochondrial branched chaim aminotransferase. In: Hancock, J. T., ed. (2008) Redox-Mediated Signal Transduction: Methods and Protocols. (Volume) Humana Press, pp. 135-148. ISBN 978-1588298423 Available from: http://eprints.uwe.ac.uk/7441

This list was generated on Sun May 29 03:32:03 2016 BST.

 

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